The .45 Pistol is a standard issue .45 calibre semi-automatic pistol. Packing a big punch from a 7 shot clip, this weapon is favoured by private security firms and government enforcement agencies.
- Colonel Joshua Starke carries a .45 Pistol when he hides in the Tenements
- The .45 Pistol is based upon the Colt M1911
- The .45 Pistol's sound effects were reused for the LX-18 in TimeSplitters: Future Perfect